Thirty years after a nuclear holocaust caused an ecocide, Eli travels on foot across the wasteland of the former United States. Wearing sunglasses and ragged clothes, he demonstrates uncanny survival and fighting skills. Searching for water, he arrives in a ramshackle town ruled by a warlord named Carnegie, who seeks to control the people through the power of a certain book, which his henchmen have been unable to find.

Eli barters with a store owner, the Engineer, to recharge the battery of his portable music player. At the town bar, he is attacked by a gang of bikers but swiftly kills them all. Impressed, Carnegie invites Eli to join his employ, but Eli declines. Realizing Eli is a literate man like himself, Carnegie forces him to stay the night under guard. Carnegie’s blind mistress Claudia brings Eli food and water and Carnegie orders her daughter Solara to seduce Eli, but he rebuffs her. Solara sees Eli has a book, and he offers to share his food, saying grace before they eat. In the morning, Carnegie overhears Solara repeating the prayer to her mother and realizes Eli has the book he has been seeking: a Bible.